oxyfluoriders
Oxyfluoriders are reagents, catalysts, or catalytic systems described in some chemical literature as capable of delivering both an oxygen-containing functionality and a fluorine atom to an organic substrate. The term is not universally standardized; some authors use it to denote dual-functionalization strategies that couple oxyfunctionalization and fluorination in a single operation or in closely linked steps. This concept is relevant to fields such as medicinal chemistry and materials science, where the presence of fluorine and oxygen functionalities can influence reactivity, polarity, metabolic stability, and binding properties.
Conceptually, oxyfluoriders may operate via two general modes: (1) concurrent transfer of oxygen and fluoride to
Applications and impact include rapid diversification of complex substrates for drug discovery, enabling late-stage installation of