oxybutynin
Oxybutynin is an antimuscarinic medication used to treat symptoms of overactive bladder, including urinary urgency, frequency, and urge incontinence. It is also used to manage neurogenic detrusor overactivity in adults. The drug works by blocking muscarinic receptors in the bladder, especially the M3 subtype, which reduces involuntary detrusor contractions and increases bladder capacity.
Common indications include symptomatic treatment of overactive bladder in adults and certain forms of neurogenic bladder.
Mechanistically, oxybutynin inhibits acetylcholine signaling in the detrusor muscle, decreasing spontaneous detrusor activity. This anticholinergic effect
Dosing varies by formulation. Immediate-release oral tablets are taken two to three times daily, with a typical
Adverse effects are mainly anticholinergic and include dry mouth, constipation, blurred vision, dizziness, and urinary retention;