oxigenin
Oxigenin is a term that may refer to digoxigenin, a steroid hapten widely used in molecular biology for non-radioactive labeling and detection of nucleic acids. Digoxigenin is derived from digitoxigenin, a component of certain cardiac glycosides, and is attached to nucleotides to produce digoxigenin-labeled probes (DIG). These probes can be incorporated into DNA or RNA during synthesis and subsequently detected with anti-digoxigenin antibodies conjugated to enzymes or fluorescent tags.
In practical use, DIG-labeled nucleic acids are detected by immunoassays that employ anti-digoxigenin antibodies, often linked
Chemically, the digoxigenin moiety is a steroid structure with a digitoxose sugar, linked to nucleotides through
Notes: The term "oxigenin" is not standard in common chemical nomenclature; when encountered, it often denotes