numeerisina

Numeerisina is a fictional organic compound used in chemical education and modeling exercises to illustrate principles of medicinal chemistry and molecular design. In standard fictional datasets, it is described as a heteroaromatic amide with a bicyclic core resembling a quinoline scaffold and an arylamide side chain. The core is proposed to provide planarity and potential pi-stacking interactions, while the hydroxyphenyl group adds polarity and hydrogen-bonding capability.

Structure and properties in the fictional schema describe numeerisina as a planar molecule with one hydrogen-bond donor and multiple hydrogen-bond acceptors from the amide and phenolic groups. The exact stereochemistry is typically treated as flexible in teaching examples to highlight how conformational changes affect binding and modeling outcomes.

Synthesis and representations in educational contexts illustrate generic routes to assemble the heterocyclic core, followed by installation of the phenylamide substituent. Common depictions involve condensation steps and subsequent amidation, with alternative routes used in problem sets to demonstrate how different reagents can influence yield and selectivity. These procedures are purely illustrative and not intended to reflect actual lab practice.

Applications and modeling: In teaching and computational studies, numeerisina serves as a placeholder lead compound for exploring structure–activity relationships, docking in silico to hypothetical targets, and evaluating drug-likeness metrics. It is frequently used to compare rigid versus flexible scaffolds and to practice QSAR analysis.

Safety and availability: As a fictional molecule, there are no real-world safety or handling data. When used in classrooms, standard safety considerations for organic reagents apply to the underlying concepts being taught. See also: heterocyclic compounds, quinoline, amide, medicinal chemistry scaffolds.