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nondividing

Nondividing is a term used in multiple disciplines to describe the absence of division, either in a biological or mathematical sense. It generally denotes a state or relation in which division does not occur.

In biology, nondividing cells are those that have exited the cell cycle and no longer undergo mitosis.

In mathematics, nondividing describes the negation of divisibility. If a and b are integers, a does not

The term nondividing is less commonly used as a formal technical label outside these contexts; it is

See also: divisibility, post-mitotic, G0 phase, divisors, prime numbers.

Such
cells
may
be
quiescent
(in
a
reversible
G0
phase)
or
permanently
post-mitotic
after
differentiation.
Examples
include
most
neurons
and
mature
cardiac
muscle
cells.
Nondividing
cells
typically
have
reduced
or
absent
capacity
to
proliferate,
relying
instead
on
maintenance,
repair,
and,
in
some
tissues,
limited
regeneration.
The
concept
is
important
for
understanding
development,
tissue
maintenance,
aging,
and
certain
diseases
where
cell
turnover
is
constrained.
divide
b
is
written
as
a
∤
b,
meaning
b
is
not
a
multiple
of
a.
For
example,
3
∤
14,
because
14
is
not
divisible
by
3.
This
usage
contrasts
with
the
positive
relation
of
divisibility,
where
a
divides
b
and
b
equals
a
multiplied
by
some
integer.
Nondivisibility
is
fundamental
in
number
theory,
affecting
properties
of
primes,
factorization,
and
modular
arithmetic.
typically
replaced
by
“does
not
divide”
in
mathematics
or
by
“post-mitotic”
or
“nonproliferating”
in
biology,
depending
on
the
domain.