mikroangiopatiaksi
Mikroangiopatiaksi refers to damage to small blood vessels, specifically arterioles and capillaries. This condition affects various organs and tissues throughout the body. The underlying causes of microangiopathy are diverse and can include metabolic disorders, autoimmune diseases, genetic conditions, and infections. A common example is diabetic microangiopathy, which develops in individuals with long-standing diabetes mellitus and can lead to complications such as retinopathy (affecting the eyes) and nephropathy (affecting the kidneys). Hypertensive microangiopathy, resulting from chronic high blood pressure, can also impair organ function. Other forms include thrombotic microangiopathies, like thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS), characterized by platelet aggregation and red blood cell destruction within small vessels. Symptoms of microangiopathy vary depending on the affected organ system. They can range from vision problems, kidney dysfunction, and neurological deficits to skin manifestations like purpura or petechiae. Diagnosis often involves a combination of clinical evaluation, laboratory tests to assess organ function and identify underlying causes, and sometimes imaging studies or biopsies. Treatment focuses on managing the underlying condition and preventing further damage to the small blood vessels.