metylkobalamiini

Metylkobalamiini is a biologically active form of vitamin B12. Vitamin B12, also known as cobalamin, is a water-soluble vitamin essential for various bodily functions. Metylkobalamiini is one of the two primary coenzyme forms of vitamin B12 found in the human body, the other being adenosylkobalamiini. It plays a crucial role in numerous metabolic processes.

This specific form of vitamin B12 is involved in the methylation cycle, a fundamental biochemical pathway. It acts as a cofactor for the enzyme methionine synthase, which is responsible for converting homocysteine into methionine. Methionine is an amino acid vital for protein synthesis and the production of S-adenosylmethionine (SAMe), a universal methyl donor required for DNA synthesis, neurotransmitter production, and energy metabolism. Metylkobalamiini also participates in the conversion of methylmalonyl-CoA to succinyl-CoA, a step in the breakdown of certain fatty acids and amino acids.

Deficiency in vitamin B12, which can lead to reduced levels of metylkobalamiini, can result in megaloblastic anemia and neurological problems. Symptoms of deficiency can include fatigue, weakness, pale skin, and neurological issues such as numbness, tingling, and cognitive difficulties. Metylkobalamiini is available as a dietary supplement and is sometimes used in the management of vitamin B12 deficiency. It is often found in multivitamin formulations and can be taken orally or sublingually.