ligandtien
Ligandtien, also known as **ligand-based drug design**, is a computational approach in pharmaceutical research that focuses on designing and optimizing drug molecules by studying their interactions with biological targets, such as proteins or enzymes. This method leverages knowledge of ligand structures—small molecules that bind to a target—to guide the development of new therapeutic compounds. By analyzing how existing ligands interact with a target, researchers can predict and refine the properties of potential drugs, including their affinity, selectivity, and efficacy.
The process typically begins with identifying a target protein or enzyme linked to a disease. Researchers then
Ligandtien is widely used in early-stage drug discovery to streamline the process by reducing reliance on trial-and-error
While effective, ligand-based drug design has limitations. It relies on existing ligand data, which may not