laktoositaluvus
Laktoositaluvus refers to the body's ability to digest lactose, the sugar found in milk and dairy products. This ability depends on lactase, an enzyme produced by enterocytes in the small intestine. Many adults experience a decline in lactase production with age, a pattern called primary lactase non-persistence, while others maintain higher lactase activity into adulthood, known as lactase persistence or lactose tolerance.
Genetic variation in the regulatory region of the LCT gene influences lactase expression. Variants promoting persistence
Primary lactase non-persistence is the most common cause of reduced lactose tolerance. Secondary lactase deficiency can
Diagnosis relies on clinical history and tests such as the hydrogen breath test or lactose tolerance test;