kinetochór
Kinetochór is a protein structure located at the centromere of a chromosome that serves as the attachment site for spindle microtubules during cell division, enabling chromosome movement and segregation. It is a multi-subunit complex organized into functional regions that interact with centromeric chromatin and with microtubules.
The kinetochór comprises an inner kinetochore assembled on centromeric chromatin containing CENP-A–containing nucleosomes, and an outer
During mitosis and meiosis, the kinetochór mediates bi-orientation by attaching sister kinetochores to microtubules from opposite
Across eukaryotes, kinetochors vary in composition and size; some organisms have holocentric kinetochores that assemble along