keratini
Keratini are a group of intermediate filaments found in the cytoplasm of epithelial cells. They are composed of keratin proteins, which are rich in alpha-helical domains. Keratini play a crucial role in the structure and function of epithelial tissues, providing mechanical strength and support. They are particularly abundant in skin, hair, nails, and certain internal epithelia such as those lining the gastrointestinal tract and respiratory system.
The primary function of keratini is to maintain the integrity of epithelial tissues. They form a network
Keratini are highly conserved proteins, with different types of keratini expressed in various tissues. For example,
In skin, keratini are responsible for the unique properties of the stratum corneum, the outermost layer of
Keratini are also involved in the process of keratinization, where epithelial cells undergo differentiation and lose
Research on keratini has implications for understanding skin diseases, hair disorders, and other epithelial-related pathologies. Mutations