intraleskaaliset

Intraleskaaliset refers to a pharmaceutical administration route where medication is injected directly into a lesion. This technique is employed in various medical fields, particularly dermatology and oncology, to deliver drugs precisely to the affected area. The primary advantage of intralesional injections is the targeted delivery of medication, which can maximize therapeutic effect at the site of the lesion while minimizing systemic exposure and potential side effects.

In dermatology, intralesional injections are commonly used to treat conditions such as keloids, hypertrophic scars, alopecia areata, and certain inflammatory dermatoses like psoriasis and lichen planus. For keloids and hypertrophic scars, corticosteroids are frequently injected intralesionally to reduce inflammation and flatten the scar tissue. For alopecia areata, corticosteroids can help stimulate hair regrowth. In oncology, intralesional chemotherapy may be used for certain superficial tumors or metastases, aiming to achieve high local drug concentrations.

The procedure typically involves using a fine needle to inject a small volume of medication directly into the dermis or subcutaneous tissue of the lesion. While generally considered safe, potential side effects can include localized pain, bruising, infection, or skin atrophy at the injection site. The specific drug and dosage are determined by the nature and size of the lesion and the condition being treated. This method offers a localized therapeutic approach for a variety of dermatological and oncological concerns.