histaminia
Histaminia is a term used in speculative physiology to describe a hypothetical syndrome characterized by dysregulation of histamine signaling in the body. The concept draws on the known roles of histamine as a mediator released by mast cells and basophils, and as a neurotransmitter acting on several receptor subtypes. In theoretical models, histaminia arises from excessive histamine release, impaired degradation, or heightened receptor sensitivity, leading to systemic or tissue-specific symptoms.
In proposed pathophysiology, increased histamine activity can affect the immune system, gastrointestinal tract, skin, and nervous
Clinical features may include episodic flushing, headaches or migraines, itching, hives, abdominal pain, diarrhea, palpitations, and
Diagnosis in the literature is not standardized; evaluation focuses on clinical history, response to antihistamines, and
Management is theoretical; in practice, approaches borrow from allergy and mast cell disorders: use of histamine
Histaminia is a speculative construct rather than a formally recognized medical diagnosis.