germlinegenredigering

Germline gene editing refers to the modification of DNA in reproductive cells (sperm and egg) or in the earliest stages of embryonic development. This means that any changes made would be heritable, passed down to future generations. The primary goal of germline gene editing is to correct genetic mutations that cause inherited diseases, thereby preventing individuals from suffering from these conditions and eliminating the disease from a family lineage.

Technologies like CRISPR-Cas9 have made germline gene editing more feasible and precise than ever before. However, the prospect of editing the human germline raises significant ethical, social, and safety concerns. These include the possibility of unintended off-target edits, the potential for creating "designer babies" with non-therapeutic enhancements, and questions about equitable access to such technologies.

Currently, germline gene editing in humans is widely prohibited for clinical applications due to these concerns and the lack of a broad societal consensus. While research is ongoing to understand its potential and limitations, the ethical debate surrounding its use remains active and complex, involving scientists, ethicists, policymakers, and the public. The international community is grappling with how to establish responsible guidelines for this powerful technology.