fluoroarenes
Fluoroarenes are aromatic compounds in which one or more hydrogen atoms on an aryl ring are replaced by fluorine. They span a range from monofluoroarenes such as fluorobenzene (C6H5F) to polyfluorinated derivatives like difluorobenzenes, trifluorobenzenes, pentafluorobenzene, and up to perfluorobenzene (C6F6).
The C–F bond is among the strongest in organic chemistry, imparting high chemical and thermal stability to
Synthesis of aryl fluorides proceeds through several general routes. Electrophilic fluorination of arenes with reagents such
Applications of fluoroarenes include roles in pharmaceuticals, agrochemicals, and advanced materials. They are also used in