créatinine

Creatinine is a chemical waste product produced by normal muscle metabolism. It is produced from the breakdown of phosphocreatine, a source of energy for muscle contraction. As creatinine is produced at a relatively constant rate by the body, it can be used as an indicator of kidney function. When the kidneys are not functioning properly, they are less able to filter creatinine out of the blood, leading to elevated levels. Blood creatinine tests are commonly performed as part of a routine physical examination or when a doctor suspects kidney problems. Urine creatinine tests can also be performed, and the ratio of creatinine to other substances in the urine can provide further diagnostic information. Factors such as age, sex, muscle mass, and diet can influence creatinine levels. For example, individuals with greater muscle mass tend to have higher creatinine levels. Certain medications can also affect creatinine levels, either by interfering with kidney function or by being metabolized into creatinine themselves. Interpreting creatinine levels requires consideration of these individual factors and should always be done in the context of a complete medical evaluation by a healthcare professional.