chemokiinien
Chemokiinien, commonly referred to in English as chemokines, are a family of small secreted cytokines that regulate the movement and positioning of cells, particularly leukocytes, by guiding them along chemical gradients. They exert their effects by binding to chemokin receptors, a subset of G protein–coupled receptors expressed on target cells, initiating signaling that directs migration, activation, and survival.
Chemokiinien are categorized by the arrangement of conserved cysteine residues near their N-terminus into four main
Biological roles of chemokiinien include recruitment of specific immune cell subsets to sites of infection or
Clinical relevance is notable because dysregulation of chemokiinien or their receptors is associated with autoimmune diseases,