chemokin
Chemokines are a family of small proteins secreted by cells that primarily act as chemoattractants, meaning they signal to and guide the migration of cells. They are crucial regulators of the immune system, playing a vital role in inflammation, immune cell trafficking, and development. Chemokines bind to specific G protein-coupled receptors, known as chemokine receptors, which are expressed on the surface of target cells. This binding initiates a cascade of intracellular signaling events that ultimately leads to directed cell movement.
The chemokine system is composed of over 50 different chemokines and roughly 20 chemokine receptors. They are
Chemokines are produced by a wide variety of cell types, including immune cells like macrophages and dendritic
Beyond their role in inflammation and immunity, chemokines are also implicated in other physiological processes, including