celltriggering
Celltriggering is the process by which cells initiate responses after stimulation by external or internal cues. It describes how an initial trigger is transduced into cellular outcomes such as altered metabolism, gene expression, secretion, or movement. Triggers can include ligand binding to receptors, mechanical forces, electrical activity, or environmental changes.
Initiating events typically involve receptors at the cell surface or in the cytoplasm. Ligand binding or other
Triggering is shaped by stimulus strength and duration, receptor density, co-stimulatory signals, and regulatory feedback. Spatial
Examples span many systems: immune activation through T-cell receptor triggering, neuronal excitation via voltage-gated ion channels
Understanding celltriggering supports drug development, immunology, neuroscience, and systems biology by clarifying how stimuli translate into