biofilmsprotective
Biofilmsprotective is a term used to describe the protective properties that microbial biofilms confer on resident cells, enabling survival under adverse conditions. The concept highlights how the extracellular polymeric substance (EPS) matrix, architectural organization, and community-wide regulatory networks limit exposure to antimicrobials, immune factors, desiccation, and shear forces. Key features include the diffusion barrier provided by EPS, metabolic heterogeneity driven by nutrient and oxygen gradients, and the presence of persister cells that tolerate lethal treatments.
Mechanisms underlying biofilmsprotective effects include reduced penetration of antimicrobial agents, altered gene expression that enhances stress
In health and industry, biofilmsprotective properties complicate treatment of device-related infections, dental plaque formation, chronic wounds,
Research on biofilmsprotective phenomena is ongoing, with aims to better characterize protective factors, model biofilm behavior,