azélaïque

Azelaic acid is a naturally occurring dicarboxylic acid found in wheat, rye, and barley. In dermatology, it is used as a topical treatment for various skin conditions, primarily acne vulgaris and rosacea. Its therapeutic benefits stem from its anti-inflammatory, antibacterial, and keratolytic properties.

When applied to the skin, azelaic acid works by reducing inflammation associated with acne. It also helps to unclog pores by decreasing the production of keratin, a protein that can contribute to pore blockage. Furthermore, it has antibacterial effects that target Cutibacterium acnes, a bacterium commonly found in acne lesions. For rosacea, azelaic acid's anti-inflammatory action helps to reduce redness and papules.

Azelaic acid is available in various concentrations, typically from 10% to 20%, as a cream, gel, or foam. Common side effects can include mild stinging, itching, redness, and peeling, which usually subside as the skin adjusts. It is generally considered safe for long-term use and is often recommended for individuals with sensitive skin who may not tolerate other acne treatments as well. It is important to use sun protection when using azelaic acid, as it can increase skin sensitivity to the sun. Its efficacy and tolerability make it a valuable option in the management of inflammatory skin conditions.