avalant

Avalant is a brand name used for venlafaxine in certain markets. Venlafaxine is an antidepressant belonging to the serotonin-norepinephrine reuptake inhibitor (SNRI) class and is prescribed for major depressive disorder, generalized anxiety disorder, social anxiety disorder, and panic disorder, among other conditions. Avalant is typically available in oral formulations, including extended-release capsules and immediate-release tablets, with strengths varying by country and product labeling.

The medication works by inhibiting the reuptake of the neurotransmitters serotonin and norepinephrine, increasing their levels in the brain to help improve mood and reduce anxiety. At higher doses, venlafaxine may affect dopamine transmission as well. The onset of clinical effect can take several weeks, and treatment often requires careful dose titration and monitoring for side effects and response.

Common side effects include nausea, dry mouth, sweating, dizziness, headache, insomnia, and sexual dysfunction. More serious but less common risks include elevated blood pressure, especially at higher doses, as well as the potential for hyponatremia, liver function changes, and an increased risk of suicidal thoughts in some individuals, particularly early in treatment or with dose changes. Abrupt discontinuation can cause withdrawal symptoms.

Contraindications include known hypersensitivity to venlafaxine or concurrent use of monoamine oxidase inhibitors (MAOIs). Caution is advised in bipolar disorder, patients with a history of mania, those with hypertension, and individuals taking other serotonergic drugs due to the risk of serotonin syndrome. Pregnancy and lactation should be discussed with a clinician, weighing potential benefits and risks. Availability and specific labeling vary by country; consult local prescribing information for details.