aquaporin4specific
Aquaporin4specific is a term used in biomedical literature to denote molecules, antibodies, or ligands that show specificity for aquaporin-4 (AQP4), a water channel protein. AQP4 is primarily expressed in the membranes of astrocyte endfeet in the central nervous system and plays a role in water homeostasis and possibly glymphatic clearance.
Most common usage refers to AQP4-specific autoantibodies, especially aquaporin-4 immunoglobulin G (AQP4-IgG). The presence of AQP4-IgG
Diagnostic methods include cell-based assays that present AQP4 on the surface of transfected cells, which offer
In research contexts, aquaporin4specific elements are used to study AQP4 distribution, function, and the role of