antiprogestogen

An antiprogestogen is a type of medication that works by blocking the effects of progesterone, a hormone crucial for the menstrual cycle and pregnancy. These drugs are primarily used in medical contexts to interrupt or manage pregnancies. The most well-known antiprogestogen is mifepristone, which is often used in combination with a prostaglandin medication to induce a medical abortion. By binding to progesterone receptors, antiprogestogens prevent progesterone from signaling the uterus to maintain a pregnancy. This disruption can lead to the breakdown of the uterine lining, causing the expulsion of the pregnancy. Beyond abortion, antiprogestogens are also being investigated and used in the treatment of certain hormone-dependent conditions such as uterine fibroids, endometriosis, and some types of cancer. Their mechanism of action allows for a targeted approach to managing conditions influenced by progesterone levels. Side effects can vary but may include bleeding, cramping, nausea, and dizziness. The use of antiprogestogens is regulated and typically requires medical supervision.