antimuszkarin
Antimuscarinic, or antimuscarinic agent, refers to a substance that antagonizes muscarinic acetylcholine receptors (M1–M5), thereby inhibiting actions of the parasympathetic nervous system. They are a subset of anticholinergic drugs used in medicine to counteract excess acetylcholine signaling.
Mechanistically, most antimuscarinics act as competitive antagonists at muscarinic receptors. By blocking M receptors in smooth
Common indications include pupil dilation for eye examinations (mydriasis) and cycloplegia, preoperative reduction of secretions, treatment
Adverse effects reflect reduced parasympathetic activity: dry mouth, blurred vision and photophobia, constipation, urinary retention, tachycardia,