Zoladex
Zoladex is the brand name for goserelin, a synthetic gonadotropin-releasing hormone (GnRH) agonist used to suppress ovarian or testicular hormone production in several conditions. It is delivered as a subcutaneous implant that releases the drug over time. Common formulations include a 3.6 mg implant given monthly and a 10.8 mg implant given every 12 weeks.
Mechanism of action: Goserelin initially stimulates GnRH receptors, causing a transient rise in luteinizing hormone (LH)
Medical uses: In advanced prostate cancer, Zoladex lowers testosterone to castration levels to slow tumor growth.
Administration and duration: Delivered by subcutaneous implant; dosing intervals depend on the formulation, typically monthly or
Side effects and risks: The most common effects include hot flashes, sweating, reduced libido, mood changes,