Wntsignalizáció
Wntsignalizáció, often referred to as the Wnt pathway, is a complex and highly conserved signaling cascade crucial for various developmental and cellular processes in multicellular organisms. This pathway plays a significant role in embryonic development, regulating cell proliferation, differentiation, cell fate determination, and cell migration. Beyond development, Wnt signaling is also implicated in adult tissue homeostasis, stem cell maintenance, and repair mechanisms. Dysregulation of Wnt signaling is strongly linked to the development and progression of numerous diseases, most notably various types of cancer, where it can promote uncontrolled cell growth and tumor formation.
There are several distinct Wnt signaling pathways, with the canonical and non-canonical pathways being the most
Non-canonical Wnt pathways, in contrast, do not involve beta-catenin accumulation and regulate processes such as planar