VEGFtekijän
VEGFtekijän, also known as vascular endothelial growth factor (VEGF), is a protein that plays a crucial role in the growth and development of blood vessels. It is a key mediator in angiogenesis, the process by which new blood vessels form from existing ones. VEGF is produced by various cell types, including endothelial cells, macrophages, and tumor cells, and it acts on endothelial cells to stimulate their proliferation, migration, and differentiation into new blood vessels.
VEGF is a member of the VEGF family, which includes several related proteins such as VEGF-A, VEGF-B,
VEGF signaling is mediated through specific receptors, known as VEGFRs (VEGF receptors). There are three main
VEGF and its receptors are involved in various physiological and pathological processes. In normal physiology, VEGF
VEGF is also a target for therapeutic interventions. Anti-VEGF agents, such as bevacizumab (Avastin) and ranibizumab