Tc99mHDP
Tc-99m hydroxymethylene diphosphonate (Tc-99m HDP) is a radiopharmaceutical used in bone scintigraphy. It consists of technetium-99m bound to a diphosphonate compound, enabling preferential uptake in bone tissue. The agent is widely used for evaluating skeletal diseases due to its ability to reflect osteoblastic activity and regional blood flow.
Mechanism and imaging characteristics
Tc-99m HDP localizes to bone by chemisorption onto hydroxyapatite crystals at sites of active bone formation
Tc-99m HDP is employed in bone scintigraphy to detect skeletal metastases, evaluate unexplained bone pain, assess
The radiopharmaceutical is given by intravenous injection. Imaging protocols, including dose and timing, vary by facility.
Technetium-99m radiopharmaceuticals; bone scintigraphy; diphosphonate imaging agents.