Sulindac

Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation associated with conditions such as arthritis, gout, and tendinitis. It works by inhibiting the cyclooxygenase (COX) enzymes, which are involved in the production of prostaglandins, substances that contribute to inflammation and pain. Sulindac is a prodrug, meaning it is converted into its active form in the body.

The typical dosage of sulindac varies depending on the condition being treated. It is usually taken orally, with or without food. Common side effects may include gastrointestinal issues such as stomach pain, nausea, and diarrhea. More serious side effects, though less common, can include ulcers, bleeding, and kidney problems. It is important to discuss potential risks and benefits with a healthcare professional before starting sulindac.

Sulindac is not recommended for individuals with a history of allergic reactions to aspirin or other NSAIDs, or for those with severe liver or kidney disease. Caution should be exercised in patients with heart disease or high blood pressure. Due to its potential to cause adverse effects, sulindac is generally prescribed for short-term use. It may interact with other medications, so it is crucial to inform your doctor about all other drugs you are taking.