Selectionranging
Selectionranging is a technique used in computational biology and bioinformatics to identify regions of a genome that are under selective pressure. This method is particularly useful in evolutionary studies, as it helps to pinpoint areas of the genome that have been conserved over time due to their functional importance. Selectionranging works by comparing the nucleotide sequences of different species to detect patterns of conservation or divergence. By analyzing these patterns, researchers can infer which regions of the genome are subject to natural selection and are therefore likely to be functionally significant. This technique is often employed in conjunction with other methods, such as phylogenetic analysis and molecular evolution models, to provide a comprehensive understanding of genetic variation and its implications for organismal fitness and adaptation. Selectionranging has been applied to a wide range of organisms, from bacteria to humans, and has contributed to numerous discoveries in fields such as medicine, agriculture, and conservation biology.