SAMtoolsBCFtools
SAMtoolsBCFtools is a command-line software package used for processing next-generation sequencing data, specifically focusing on variant calling and manipulation. It is a collection of tools derived from the original SAMtools and BCFtools projects, now integrated into a single suite. The package is widely used in bioinformatics for its efficiency and comprehensive functionality in analyzing genomic variations.
The core components of SAMtoolsBCFtools enable users to convert sequence alignment files (such as SAM and BAM
Beyond basic variant calling, SAMtoolsBCFtools offers advanced features for manipulating and filtering variant calls. Users can