SAMban

SAMban is a software package designed for the analysis of next-generation sequencing (NGS) data, with a particular focus on the detection of structural variations (SVs) in genomes. It is an open-source tool developed by the Bioinformatics Research Center at the National Institute of Advanced Industrial Science and Technology (AIST) in Japan. SAMban operates on the SAM/BAM format, which is a standard format for storing large NGS alignments. The software is capable of identifying various types of SVs, including insertions, deletions, inversions, and translocations. It employs a combination of read-depth analysis and split-read mapping to detect these variations. SAMban is known for its high accuracy and sensitivity in SV detection, making it a valuable tool for researchers studying genomic rearrangements. The software is available for download from the AIST's official website and is distributed under the GNU General Public License.