RPL35A

RPL35A, also known as ribosomal protein L35A, is a gene that encodes a component of the large 60S ribosomal subunit. Ribosomes are essential cellular machinery responsible for protein synthesis, translating messenger RNA (mRNA) into polypeptide chains. RPL35A is a member of the ribosomal protein L35 family and is one of the 82 ribosomal proteins found in eukaryotes.

The protein plays a crucial role in the proper assembly and function of the 60S ribosomal subunit, which works in conjunction with the 40S subunit to form a complete, active ribosome. This protein is highly conserved across various species, suggesting its fundamental importance in cellular life.

Studies have indicated that alterations or dysregulation of RPL35A expression can be associated with certain diseases, including various types of cancer. For instance, some research suggests that RPL35A may function as a tumor suppressor or an oncogene depending on the cellular context and specific cancer type. Its role in cancer is an active area of ongoing investigation, with potential implications for diagnostic markers and therapeutic strategies. Further research is needed to fully elucidate the complex functions and disease associations of RPL35A.