QuEChERS
QuEChERS, which stands for Quick, Easy, Cheap, Effective, Rugged, and Safe, is a sample preparation method developed in 2003 by a collaboration between the United States Department of Agriculture (USDA) and the Netherlands Food and Consumer Product Safety Authority (NVWA). The technique was originally designed for the extraction of pesticide residues from fruits and vegetables but has since been adapted for a broad range of analytes, including mycotoxins, veterinary drug residues, and environmental contaminants.
The core of the QuEChERS method involves mixing a homogenized food sample with an acetonitrile-based extraction
The appealing attributes of QuEChERS—low reagent use, minimal equipment, rapid turnaround, and compatibility with high‑throughput liquid
Limitations of QuEChERS include its less effective performance for highly polar or volatile compounds and the