Paeoniflorin

Paeoniflorin is a naturally occurring monoterpene glycoside found in plants of the Paeonia genus, commonly known as peonies. It is the primary active component of peony root, particularly from Paeonia lactiflora, which has a long history of use in traditional Chinese medicine.

Chemically, paeoniflorin is characterized by a glucoside structure, meaning a sugar molecule (glucose) is attached to a non-sugar molecule (aglycone). Its molecular formula is C23H28O11. It typically appears as a white crystalline powder and is soluble in water and ethanol.

Research into paeoniflorin has explored its potential pharmacological activities. Studies have indicated it possesses anti-inflammatory, antioxidant, analgesic, and immunomodulatory properties. These effects are thought to be mediated through various mechanisms, including the inhibition of pro-inflammatory cytokines and the scavenging of free radicals.

In traditional medicine, peony root, rich in paeoniflorin, has been used to treat a variety of conditions, including menstrual irregularities, pain, and inflammatory diseases. Modern scientific investigations are ongoing to validate these traditional uses and to further understand the therapeutic potential of paeoniflorin in various health contexts. Its isolation and study contribute to the ongoing exploration of phytochemistry and the development of natural-based pharmaceuticals.