PCSK9remmers
PCSK9 inhibitors are a class of drugs used to lower low-density lipoprotein (LDL) cholesterol levels. They work by targeting a protein called PCSK9 (proprotein convertase subtilisin/kexin type 9). This protein plays a role in regulating the number of LDL receptors on the surface of liver cells. LDL receptors are responsible for removing LDL cholesterol from the bloodstream. PCSK9 binds to these receptors and leads to their degradation, thus reducing the liver's ability to clear LDL cholesterol.
PCSK9 inhibitors, typically monoclonal antibodies, bind to PCSK9 and prevent it from interacting with LDL receptors.
These medications are usually administered via subcutaneous injection, with dosing schedules varying depending on the specific