Orphanet
Orphanet is a European reference portal dedicated to information on rare diseases and orphan drugs. It provides high-quality, freely accessible information to improve diagnosis, care, and research for rare conditions. Each disease entry is assigned a unique Orpha number and cross-referenced with ICD classifications and genetic information to help standardize terminology and reporting.
The Orphanet database covers disease descriptions, inheritance patterns, clinical signs, differential diagnoses, diagnostic tests, management options,
Orphanet serves as a resource for clinicians, researchers, patients, and policymakers. It supports new drug development
Governance and funding have evolved since its inception in the late 1990s. Orphanet began as a European