Orgasmin

Orgasmin is a term that has appeared in speculative writings to denote a hypothetical chemical associated with orgasm. In these contexts it is described as a potential pheromone or neuromodulator produced during sexual arousal or orgasm and capable of influencing physiology or behavior in others, or reinforcing sexual motivation in the individual. However, orgasmin is not a recognized substance in established chemistry or physiology.

In scientific practice, there is no peer‑reviewed evidence for the existence of orgasmin as a defined molecule. No experimentally determined structure, biosynthetic pathway, receptor target, or reproducible measurements have been reported, and major databases do not list an orgasmin. The term is occasionally encountered in popular articles or fiction as a speculative concept, but it does not form part of accepted explanations of sexual physiology.

History and usage: The term originated in sensational or popular outlets and has largely fallen out of use in serious scientific literature. When it appears today, orgasmin is typically treated as a hypothetical or fictional construct rather than a real biochemical entity.

See also: Pheromones, hormones, neuromodulators, sexual arousal.