Normoalbuminurie

Normoalbuminurie, also called normoalbuminuria, refers to a normal amount of albumin excreted in the urine. It is typically defined as an albumin excretion rate (AER) of less than 30 milligrams per day or an albumin-to-creatinine ratio (ACR) in a spot urine sample of less than 30 milligrams per gram creatinine. Values may vary slightly between laboratories.

Normal albumin excretion indicates an intact glomerular filtration barrier and preserved kidney function. However, a lack of albuminuria does not exclude kidney disease or cardiovascular risk. In people with diabetes or hypertension, screening for albuminuria helps identify early renal involvement and risk stratification. When albuminuria progresses to microalbuminuria (approximately 30–300 mg/day) or macroalbuminuria (over 300 mg/day), renal injury and cardiovascular risk are higher.

Several factors can transiently influence albumin measurements, including recent strenuous exercise, fever, dehydration, urinary tract infection, or high protein intake. If results are elevated or inconsistent, repeat testing is recommended.

For individuals at risk, regular monitoring is advised. If albuminuria is detected, management focuses on risk factor control and renal protection, including blood pressure and glycemic control and avoidance of nephrotoxins. In many patients, medications such as renin–angiotensin–aldosterone system (RAAS) blockers and, in diabetes, SGLT2 inhibitors, can reduce albuminuria and help protect renal function.