Neogenese

Neogenese is a term used in some scientific contexts to denote the process of origin or formation of new tissues, cells, or structures. It is a variant spelling of neogenesis, from Greek neo- "new" and genesis "origin" or "creation." In English-language biology, the standard forms are neogenesis or neurogenesis when referring to the formation of new neurons specifically.

In developmental biology and regenerative medicine, neogenese describes the formation of new tissue from stem or progenitor cells, as distinct from hypertrophy (growth by enlargement of existing cells) or hyperplasia (increased cell number). The concept covers processes such as tissue regeneration, organogenesis from stem cells, and the replacement of damaged cells through differentiation. Specific examples include neurogenesis in the adult brain, adipose tissue neogenesis linked to fat mass remodeling, and hepatocyte neogenesis during liver regeneration, though terminology can vary by field and language.

Because neogenese is more commonly encountered in non-English texts, English writers generally prefer neogenesis, neurogenesis, or tissue neogenesis. The spelling can reflect translation from German, Dutch, or Romance-language sources, where the root terms are widely used. Overall, neogenese describes the broader idea of creating new tissue or cell types rather than simply enlarging existing ones, and is closely related to but distinct from developmental biology terms of organogenesis and regeneration.

See also: neogenesis, neurogenesis, tissue regeneration, adipogenesis.