Metabotropické
Metabotropic refers to a type of receptor in cell signaling that is indirectly activated by a neurotransmitter or hormone. Unlike ionotropic receptors, which directly open ion channels when bound by a ligand, metabotropic receptors initiate a cascade of intracellular events. This cascade typically involves a G protein, a molecule that then influences the activity of other enzymes or ion channels within the cell. This indirect mechanism leads to a slower but often more prolonged and diverse cellular response compared to ionotropic receptors.
The activation of a metabotropic receptor begins when its corresponding ligand binds to the extracellular portion
Metabotropic receptors play crucial roles in numerous physiological processes, including neurotransmission, hormone action, and sensory perception.