MRTLäsionen

MRTLäsionen, which translates to "Multiple Sclerosis Lesions" in English, refers to the characteristic areas of damage that occur in the central nervous system of individuals with Multiple Sclerosis (MS). These lesions, also known as plaques or demyelinating lesions, are primarily found in the white matter of the brain and spinal cord. They are caused by the immune system mistakenly attacking the myelin sheath, the protective covering around nerve fibers. This attack leads to inflammation and the breakdown of myelin, a process called demyelination.

The appearance of MRTLäsionen on magnetic resonance imaging (MRI) is a key diagnostic tool for MS. They typically appear as bright spots on T2-weighted or FLAIR sequences. The location, size, and number of these lesions can vary significantly between individuals and can evolve over time. Lesions can occur in various parts of the central nervous system, including the periventricular white matter, corpus callosum, brainstem, cerebellum, and spinal cord.

The presence and characteristics of MRTLäsionen are closely correlated with the symptoms experienced by individuals with MS. Depending on their location, lesions can disrupt the transmission of nerve signals, leading to a wide range of neurological symptoms such as fatigue, numbness, tingling, muscle weakness, vision problems, balance difficulties, and cognitive impairment. The development of new lesions or the enlargement of existing ones often corresponds to relapses or a progression of the disease. Monitoring these lesions through serial MRI scans is crucial for assessing disease activity, evaluating treatment effectiveness, and predicting disease course.