Löslighetsprofil
Löslighetsprofil refers to the characterization of a substance's solubility behavior across a range of conditions, most commonly varying pH values. It is a crucial concept in pharmaceutics, chemistry, and environmental science. In the context of pharmaceuticals, understanding a drug's solubility profile is essential for predicting its absorption, distribution, metabolism, and excretion (ADME) properties within the body. A drug that exhibits poor solubility across a wide pH range may have limited bioavailability.
A solubility profile is typically determined experimentally by measuring the concentration of a substance that can
The data generated from solubility profiling can be visualized in a graph, plotting solubility against pH.