LuriaDelbrückmodellen
The Luria-Delbrück model, also known as the fluctuation test, is a foundational concept in the field of molecular biology and genetics that explains the origin of spontaneous mutations. Proposed by Salvador Luria and Max Delbrück in 1943, the model addresses how bacterial resistance to bacteriophages arises. Prior to this model, it was commonly believed that mutations were induced by external factors or were a direct response to environmental pressure.
The Luria-Delbrück model posits that mutations occur randomly and spontaneously, independent of the selective agent. In
The model explains this variation by suggesting that mutations conferring resistance happened at different times in
This understanding was revolutionary because it demonstrated that the environment acts as a selective force on