LuriaDelbrück
Luria-Delbrück refers to a landmark experiment in bacterial genetics conducted by Salvador E. Luria and Max Delbrück in the early 1940s. The work demonstrated that genetic mutations arise spontaneously and in a random, preexisting manner rather than being induced by exposure to a selective agent. This finding supported the random-mutation theory of genetic variation and helped establish the modern understanding of how mutations contribute to evolution.
In the core experiment, multiple independent cultures of Escherichia coli were grown in parallel and then challenged
Interpreting the fluctuations, Luria and Delbrück argued that resistance mutations occurred randomly during growth and were
The experiment introduced the fluctuation test and the concept now known as the Luria-Delbrück distribution. It