Hormonreceptorpozitív

Hormonreceptorpozitív is a term used in medicine, particularly in oncology, to describe cancer cells that have specific protein receptors on their surface or within the cell that can bind to hormones. The most common types of hormone receptors tested for are estrogen receptors (ER) and progesterone receptors (PR). When these receptors are present and active, the cancer is classified as hormone receptor-positive or hormone-sensitive.

Hormone receptor-positive cancers, most notably breast cancer, are influenced by hormones like estrogen and progesterone. These hormones can stimulate the growth and proliferation of the cancer cells. Identifying whether a cancer is hormone receptor-positive is crucial for determining the most effective treatment strategies.

Treatments for hormone receptor-positive cancers often involve therapies that block the action of these hormones or reduce their levels in the body. This can include medications such as tamoxifen, aromatase inhibitors (like anastrozole, letrozole, and exemestane), or fulvestrant. By targeting the hormonal drivers of cancer growth, these treatments can help slow or stop the disease's progression.

The presence or absence of hormone receptors is typically determined through laboratory tests performed on a sample of the tumor tissue, usually obtained during a biopsy. This information is a key factor in the staging and treatment planning for many types of cancer, especially breast cancer. A positive result for ER or PR indicates that hormonal therapy is a likely and often effective treatment option.