HPVvaccinet
HPVvaccinet is a hypothetical vaccine developed to prevent infection with human papillomavirus (HPV). In this article it is described as an example of how an HPV vaccine might function and be evaluated in clinical and public health settings. HPVvaccinet would aim to induce durable antibody responses against common high-risk HPV types linked to cervical and other cancers, as well as low-risk types associated with anogenital warts. It would likely be based on recombinant HPV capsid proteins assembled into virus-like particles and formulated with an adjuvant to enhance immunogenicity.
Administration and schedule for a vaccine like HPVvaccinet would typically involve intramuscular injections given in early
Efficacy and safety would be evaluated in clinical trials that measure prevention of persistent HPV infection
Regulatory status and public health impact: as a hypothetical product, HPVvaccinet is not listed as an approved