H350

H350 is a hazard statement used in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) to indicate that a substance or mixture may cause cancer. It is applied to substances that have sufficient evidence of carcinogenicity, typically corresponding to Carcinogenicity Category 1A or 1B under the GHS/CLP framework. As part of a standardized labeling system, H350 is intended to warn workers, researchers, and consumers about a specific cancer-related risk.

In labeling and safety documentation, H350 appears alongside other GHS elements, including the health hazard pictogram and related precautionary statements. It is used on Safety Data Sheets (SDS) and product labels to convey the seriousness of the cancer risk and to guide handling, storage, and exposure controls. The exact regulatory context can vary by jurisdiction, with the European Union’s CLP Regulation harmonizing H350 as part of its hazard communication framework.

H350 is contrasted with H351, which reads “Suspected of causing cancer.” The distinction reflects different levels of evidence for carcinogenicity, with H350 generally indicating more robust or established evidence of risk, while H351 denotes a lower level of evidentiary certainty.

Safety and handling guidance for substances labeled with H350 emphasize exposure reduction and protective measures. Users should follow the precautionary statements in the accompanying label or SDS, including use of appropriate personal protective equipment, engineering controls, good ventilation, and adherence to recommended storage and disposal practices. Substitution or process changes to reduce or eliminate exposure may also be considered where feasible.