Gproteinkoblete
Gproteinkoblete is a proposed regulatory module in eukaryotic G protein signaling. Described in a small body of proteomics and biochemical studies, it is characterized as a multi-subunit complex that associates with heterotrimeric G proteins following receptor activation. The concept posits that Gproteinkoblete influences the nucleotide state of Gα subunits and thereby modulates downstream signaling pathways, potentially adding a layer of control separate from classical GPCR-mediated activation.
Composition and structure are described in the available reports as consisting of two core subunits, referred
Function and mechanism are presented as follows: Gproteinkoblete is thought to act as a non-catalytic regulator
Localization and regulation are described as membrane-associated, with potential modulation by phosphorylation or lipid binding. While